Can I use XMP profiles to automatically configure my DDR4 memory?

Yes, the motherboard supports Intel Extreme Memory Profile (XMP) technology. In the BIOS Ai Tweaker menu, you can select either [XMP I] to load DIMM default XMP memory timings with optimized BCLK frequency, or [XMP II] to load the complete default XMP profile for memory modules that support this technology.

From the official ASUS Asus Prime Z390 A Motherboard User manual, page 77

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