How do I adjust the temperature setpoint on my Honeywell Pro Series thermostat?
Use the up and down arrow buttons on the thermostat display to raise or lower the temperature setpoint to your desired level. The current temperature and setpoint will display on the screen. Changes take effect immediately unless you are in a programmed schedule mode, in which case the next scheduled change will override manual adjustments.
From the official Honeywell Thermostat Pro Series manual, page 1
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