Does the Signature M650 For Business mouse work on Linux or Chrome OS without installing software?

Yes, basic device functions are supported on Linux and Chrome OS without requiring Logi Options+ software. However, advanced features such as button customization require Logi Options+ software on Windows 10 or macOS 10.15 or later. (Page 2)

From the official Logitech M650 Full Size Wireless Mouse manual, page 2

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